3 cases of children identified in Greece

In Greece, three children with symptoms of acute hepatitis were detected, the National Medical Institution EODY announced Thursday afternoon. This is the first case of acute hepatitis in children in the country.

In a statement, EODY identified three cases of acute hepatitis in children who met the criteria of “according to the definition of the World Health Organization” and “potential cases” as a result of an aggressive case study.

According to the announcement, two children, 14 months and 10 years old, showed gastrointestinal symptoms (abdominal pain and vomiting) and fever, and laboratory tests showed increased liver enzymes (transaminase> 500 IU / ml).

The third case, an 18-month-old child, was asymptomatic and prophylactic laboratory tests showed increased liver enzymes.

Testing for viral hepatitis AE was negative in all three children.

EBV, CMV, adenovirus, and SARS-CoV-2 virus were not detected by any other laboratory test.

Two of the three children needed to be hospitalized for several days.

The children show no complications, have not received special treatment, and are in good general condition.

In that statement, EODY did not reveal the children’s residential areas or the hospitals they were treated for.

Last month, health officials “Suspicious” cases of acute hepatitis.. Ultimately, a 9-year-old child in Athens did not develop a mysterious illness.

Watching authorities and doctors

“Clinicians are wary of this new situation, providing information and vigilance to timely detect children up to the age of 16 who are showing signs or symptoms of hepatitis for no apparent reason. In such cases, please fill out and send. EODY is a declaration, “added the statement.

EODY carefully monitors the development of the situation, systematically contacts the European Public Health Organization, the European Center for Disease Control and Control (ECDC) and the World Health Organization (WHO), and has already provided information to all health areas of the country. I am. .. , Panhellenic Medical Association, and scientific associations whose members may face similar incidents.

Instructions were sent to collect samples and send them to the Central Public Health Institute to immediately implement the controls necessary to identify the cause of the outbreak, “the statement emphasized.

Epidemiology of acute hepatitis worldwide

According to EODY’s announcement, an unusually large number of cases of acute hepatitis were observed in children in the United Kingdom in early April. No cases of hepatitis virus infection (A to E) were recorded and no correlation was found with travel or exposure to toxic substances or environmental factors.

Clinical syndromes occur in children up to 16 years, most often 2-5 years, with markedly elevated transaminase, including severe acute hepatitis with jaundice and gastrointestinal symptoms (main symptoms of vomiting). increase. jaundice.

Following the announcement of the case by the United Kingdom, similar cases have been reported not only in 16 European countries, but also in the United States, Canada, Japan, Israel and Singapore. The total number of cases in the world is very small.

To date, approximately 300 cases have been reported, of which 163 have been reported from the United Kingdom.

Although the number of suspected cases has been added, the number of cases in each country does not seem to increase, suggesting that the spread is limited.

Most children required hospitalization, some required transfer to a specialized pediatric liver disease unit, and only a few received liver transplants.

Since the beginning of 2022, the root cause of this increase remains unknown. Further laboratory investigations are underway in cases identified for additional infections, chemicals and toxins.

Source: EODY 3 cases of children identified in Greece

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