A small study suggests that the placenta may have ways to protect itself and the foetation from infection with the coronavirus.
The researchers studied 24 women who gave birth between July 2020 and April 2021.
When Covid-19 occurs during pregnancy, especially late in pregnancy, placental cells “flush” a surface protein called ACE2, which the virus uses to invade and infect cells, reducing the gateway for entry. It looked like.
Women who had Covid-19 in late pregnancy had high levels of an enzyme called ADAM17, which is known to help ACE2 release itself from the cell surface, researchers report. Did American Journal of Pathology..
The placenta may be sensing Maternal Covid-19 infection, “introducing this mechanism to shed ACE2 and prevent SARS-CoV-2 from invading the placenta and infecting the foetation. “Maybe,” said Elizabeth Taglauer of the Boston Medical Center. ..
Previous studies have shown that placental cells are infected in about 7% to 20% of pregnancies in which mothers are infected with Covid-19, according to Taglauer.
She added that if the virus somehow invades the placenta, it rarely reaches the foetation. Her team plans to further study “protective pathways” that can keep the virus away from placental cells and fetal blood vessels.
Last updated: February 3, 2022 11:08 AM
http://www.gulf-times.com/story/709204/Placenta-may-have-mechanism-that-protects-fetus-fr The placenta may have a mechanism to protect the foetation from covid