Turquie researchers’ UK study sheds light on treatment of metabolic disease – Middle East Monitor

Hundreds of new proteins discovered by a British team led by Turkish scientist Mine Koprul offer hope in the development of new treatments and drugs for many metabolic diseases such as diabetes and multiple sclerosis (MS). has become light. Anadolu Agency report.

Gates Cambridge, who offers scholarships to successful graduate students at the University of Cambridge and Koprul is one of its scholars, shared the research led by the Turkish scientist on his Twitter account.

Koprulu is leading research that “identifies proteogenomics data that may lead to new treatments for diseases such as diabetes,” said Gates Cambridge.

Turkish scientist said Anadolu What makes this study so different from other studies is that it “used a new technology developed for the first time in the world to measure the levels of 3,000 proteins in parallel from people’s blood samples and integrated them into the study. .”

She pointed out that the biological mechanisms underlying many metabolic diseases that are so common in society, such as diabetes, blood pressure, heart disease, and kidney disease, are largely unknown.

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“We actually systematically analyzed protein levels of 3,000 proteins in the blood, DNA changes, the genetic code and the risk of hundreds of diseases to precisely address this question,” she says. said.

Saying the purpose of the study is to shed light on finding more effective drugs and treatments for the disease, the young scientist said: Our current study focuses on the triad of alterations, protein levels, and disease risk.”

“I hope this will be the first step toward finding more advanced treatments for hundreds of diseases,” she added.

Citing the study’s key findings, Koprulu said that he found that high levels of a hormone called GRP reduced the risk of diabetes, and that he also reduced the risk of MS disease with a newly discovered protein called DKKL1. I pointed out that they are related. is not a lot of information.

Koprulu stated that he completed his Bachelor’s degree in Human Genetics from University College London, where he was educated, and then received his Master’s degree in Medical Genetics from the University of Cambridge.

She also said she has been working on rare disease genetics for two years at Bogazici University in Turkiye and Istanbul Technical University.

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