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Shorter programs of radiotherapy more and more used for prostate most cancers

From 2004 to 2020, there was a rise in using shorter radiotherapy (RT) programs (hypofractionation) for prostate most cancers, in response to a quick report printed on-line Oct. 5 in JAMA Oncology.

James B. Yu, M.D., from St. Francis Hospital in Hartford, Connecticut, and colleagues used information from the Nationwide Most cancers Database to determine the present apply patterns of exterior beam RT for prostate most cancers in the USA. The evaluation included 313,062 sufferers with localized prostate most cancers.

The researchers recognized a major temporal sample of decline within the proportion of sufferers who acquired typical fractionation from 2004 to 2020 (76.0 to 36.6 %). Throughout the identical interval, use of reasonable hypofractionation and ultrahypofractionation considerably elevated (from 22.0 to 45.0 % and from 2.0 to 18.3 %, respectively).

For sufferers within the low- and intermediate-risk teams, the commonest RT schedule by 2020 was ultrahypofractionation and reasonable hypofractionation, respectively. Shorter programs of RT had been seen in affiliation with therapy at a group most cancers program versus educational or analysis program, Medicaid versus Medicare insurance coverage, Black versus White race, and better versus decrease median revenue.

“Lowered adoption was related to a number of social determinants of well being,” the authors write. “Realignment of value-based fashions to appropriately improve reimbursement for hypofractionation might cut back limitations to nationwide adoption and will guarantee entry to this therapy for underserved communities.”

A number of authors disclosed ties to the pharmaceutical business.

Extra data:
James B. Yu et al, Growing Use of Shorter-Course Radiotherapy for Prostate Most cancers, JAMA Oncology (2023). DOI: 10.1001/jamaoncol.2023.4267

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